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Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion
Elevated expression levels of the apurinic/apyrimidinic endonuclease 1 (APE1) have been correlated with the more aggressive phenotypes and poor prognosis of non-small cell lung cancer (NSCLC). This study aimed to assess the impact of the inhibition of the redox function of APE1 with E3330 either alo...
Autores principales: | Manguinhas, Rita, Fernandes, Ana S., Costa, João G., Saraiva, Nuno, Camões, Sérgio P., Gil, Nuno, Rosell, Rafael, Castro, Matilde, Miranda, Joana P., Oliveira, Nuno G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346157/ https://www.ncbi.nlm.nih.gov/pubmed/32599967 http://dx.doi.org/10.3390/antiox9060550 |
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