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Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats

Cardiac β-adrenergic overstimulation results in oxidative stress, hypertrophy, ischemia, lesion, and fibrosis rendering the heart vulnerable to malignant arrhythmias. We aimed to explore the anti-arrhythmic efficacy of the anti-oxidative and anti-inflammatory compounds, melatonin, and omega-3, and t...

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Detalles Bibliográficos
Autores principales: Szeiffova Bacova, Barbara, Viczenczova, Csilla, Andelova, Katarina, Sykora, Matus, Chaudagar, Kiranj, Barancik, Miroslav, Adamcova, Michaela, Knezl, Vladimir, Egan Benova, Tamara, Weismann, Peter, Slezak, Jan, Tribulova, Narcisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346184/
https://www.ncbi.nlm.nih.gov/pubmed/32580481
http://dx.doi.org/10.3390/antiox9060546