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Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors

[Image: see text] The development of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is an ongoing and challenging research field. However, the dynamic motion of the binding site of EGFR has not been accurately depicted, hindering the improvement of EGFR TKI. For this reas...

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Detalles Bibliográficos
Autores principales: Li, Dong-Dong, Wu, Ting-Ting, Yu, Pan, Wang, Zhen-Zhong, Xiao, Wei, Jiang, Yan, Zhao, Lin-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346266/
https://www.ncbi.nlm.nih.gov/pubmed/32656454
http://dx.doi.org/10.1021/acsomega.0c02183