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Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers

[Image: see text] Pathogenesis of Alzheimer’s disease (AD), the most common type of dementia, involves misfolding and aggregation of the extracellular amyloid-β (Aβ) protein where the intermediate oligomers, formed during the aggregation progression cascade, are considered the prime toxic species. H...

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Detalles Bibliográficos
Autores principales: Bhattacharyya, Rajanya, Bhattacharjee, Sayan, Pathak, Bani K., Sengupta, Jayati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346273/
https://www.ncbi.nlm.nih.gov/pubmed/32656435
http://dx.doi.org/10.1021/acsomega.0c01730