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Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway

BACKGROUND: C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has been shown to inhibit cellular proliferation and induce apoptosis of various c...

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Detalles Bibliográficos
Autores principales: Gu, Jianyou, Zhang, Yu, Wang, Xiao, Xiang, Jingjing, Deng, Shu, Wu, Dijiong, Chen, Junfa, Yu, Lihong, Zhou, Yan, Wang, Yaokun, Shen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346655/
https://www.ncbi.nlm.nih.gov/pubmed/32641029
http://dx.doi.org/10.1186/s12906-020-03006-2