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Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway
BACKGROUND: C-Myc overexpression is associated with poor prognosis and aggressive progression of natural killer/T-cell lymphoma (NKTCL). Matrine, a main alkaloid of the traditional Chinese herb Sophora flavescens Ait, has been shown to inhibit cellular proliferation and induce apoptosis of various c...
Autores principales: | Gu, Jianyou, Zhang, Yu, Wang, Xiao, Xiang, Jingjing, Deng, Shu, Wu, Dijiong, Chen, Junfa, Yu, Lihong, Zhou, Yan, Wang, Yaokun, Shen, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346655/ https://www.ncbi.nlm.nih.gov/pubmed/32641029 http://dx.doi.org/10.1186/s12906-020-03006-2 |
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