EGR2 is elevated and positively regulates inflammatory IFNγ production in lupus CD4(+) T cells

BACKGROUND: Recent studies have shown that early growth response 2 (EGR2) is highly induced in activated T cells and regulates T cell functions. In normal C57BL/6 (B6) mice, deletion of EGR2 in lymphocytes results in the development of lupus-like systemic autoimmune disease, which implies indirectly...

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Detalles Bibliográficos
Autores principales: Dai, Rujuan, Heid, Bettina, Xu, Xiguang, Xie, Hehuang, Reilly, Christopher M., Ahmed, S. Ansar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346656/
https://www.ncbi.nlm.nih.gov/pubmed/32646370
http://dx.doi.org/10.1186/s12865-020-00370-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346656/
https://www.ncbi.nlm.nih.gov/pubmed/32646370
http://dx.doi.org/10.1186/s12865-020-00370-z

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