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EGR2 is elevated and positively regulates inflammatory IFNγ production in lupus CD4(+) T cells
BACKGROUND: Recent studies have shown that early growth response 2 (EGR2) is highly induced in activated T cells and regulates T cell functions. In normal C57BL/6 (B6) mice, deletion of EGR2 in lymphocytes results in the development of lupus-like systemic autoimmune disease, which implies indirectly...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346656/ https://www.ncbi.nlm.nih.gov/pubmed/32646370 http://dx.doi.org/10.1186/s12865-020-00370-z |