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Asymmetric Rab activation of vacuolar HOPS to catalyze SNARE complex assembly

Intracellular membrane fusion requires Rab-family GTPases, their effector tethers, soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins, and SNARE chaperones of the Sec1/Munc18 (SM), Sec17/α-SNAP, and Sec18/NSF families. We have developed an assay using fluorescence...

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Detalles Bibliográficos
Autores principales: Torng, Thomas, Song, Hongki, Wickner, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346727/
https://www.ncbi.nlm.nih.gov/pubmed/32160129
http://dx.doi.org/10.1091/mbc.E20-01-0019