WNT974 Inhibits Proliferation, Induces Apoptosis, and Enhances Chemosensitivity to Doxorubicin in Lymphoma Cells by Inhibiting Wnt/β-Catenin Signaling

BACKGROUND: Upregulation of the Wnt/β-catenin pathway has been demonstrated to promote tumor proliferation and chemoresistance in lymphoma. Our objective was to evaluate the effect of the Wnt/β-catenin pathway inhibitor WNT974 in lymphoma cells. MATERIAL/METHODS: Human lymphoma cell lines HUT-78 and...

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Detalles Bibliográficos
Autores principales: Chen, Senmin, Yuan, Xiuli, Xu, Huanli, Yi, Meng, Liu, Sixi, Wen, Feiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346748/
https://www.ncbi.nlm.nih.gov/pubmed/32597418
http://dx.doi.org/10.12659/MSM.923799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346748/
https://www.ncbi.nlm.nih.gov/pubmed/32597418
http://dx.doi.org/10.12659/MSM.923799

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