Safety and immunogenicity of experimental stand-alone trivalent, inactivated Sabin-strain polio vaccine formulations in healthy infants: A randomized, observer-blind, controlled phase 1/2 trial

BACKGROUND: To increase the global supply of affordable IPV vaccine, preferably using Sabin viruses to comply with GAPIII requirements, Takeda has assessed three dosages of a stand-alone sIPV. METHODS: In this phase I/II study two cohorts of 40 adults and 60 toddlers, respectively, were initially as...

Descripción completa

Detalles Bibliográficos
Autores principales: Cramer, Jakob P., Jimeno, José, Han, Htay Htay, Lin, Stella, Hartmann, Katharina, Borkowski, Astrid, Sáez-Llorens, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347011/
https://www.ncbi.nlm.nih.gov/pubmed/32563609
http://dx.doi.org/10.1016/j.vaccine.2020.05.081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347011/
https://www.ncbi.nlm.nih.gov/pubmed/32563609
http://dx.doi.org/10.1016/j.vaccine.2020.05.081

Ejemplares similares