Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila

In most organisms, dietary restriction (DR) increases lifespan. However, several studies have found that genotypes within the same species vary widely in how they respond to DR. To explore the mechanisms underlying this variation, we exposed 178 inbred Drosophila melanogaster lines to a DR or ad lib...

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Detalles Bibliográficos
Autores principales: Jin, Kelly, Wilson, Kenneth A., Beck, Jennifer N., Nelson, Christopher S., Brownridge, George W., Harrison, Benjamin R., Djukovic, Danijel, Raftery, Daniel, Brem, Rachel B., Yu, Shiqing, Drton, Mathias, Shojaie, Ali, Kapahi, Pankaj, Promislow, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347105/
https://www.ncbi.nlm.nih.gov/pubmed/32644988
http://dx.doi.org/10.1371/journal.pgen.1008835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347105/
https://www.ncbi.nlm.nih.gov/pubmed/32644988
http://dx.doi.org/10.1371/journal.pgen.1008835

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