Cargando…

MECHANISMS GENERATING CANCER GENOME COMPLEXITY FROM A SINGLE CELL DIVISION ERROR

The chromosome breakage-fusion-bridge (BFB) cycle is a mutational process that produces gene amplification and genome instability. Signatures of BFB cycles can be observed in cancer genomes alongside chromothripsis, another catastrophic mutational phenomenon. Here, we explain this association by elu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Umbreit, Neil T., Zhang, Cheng-Zhong, Lynch, Luke D., Blaine, Logan J., Cheng, Anna M., Tourdot, Richard, Sun, Lili, Almubarak, Hannah F., Judge, Kim, Mitchell, Thomas J., Spektor, Alexander, Pellman, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347108/ https://www.ncbi.nlm.nih.gov/pubmed/32299917 http://dx.doi.org/10.1126/science.aba0712

Ejemplares similares

Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing
por: Leibowitz, Mitchell L., et al.
Publicado: (2021)

Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
por: Papathanasiou, Stamatis, et al.
Publicado: (2021)

Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements
por: Zhang, Cheng-Zhong, et al.
Publicado: (2013)

CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI
por: Zhang, Cheng-Zhong, et al.
Publicado: (2015)

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor
por: Jiao, Alan L., et al.
Publicado: (2019)

DNA breaks and chromosome pulverization from errors in mitosis
por: Crasta, Karen, et al.
Publicado: (2012)

The complexity of divisibility
por: Bausch, Johannes, et al.
Publicado: (2016)

The first mitotic division of human embryos is highly error prone
por: Currie, Cerys E., et al.
Publicado: (2022)

Nuclear envelope assembly defects link mitotic errors to chromothripsis
por: Liu, Shiwei, et al.
Publicado: (2018)

The Ndc80 complex bridges two Dam1 complex rings
por: Kim, Jae ook, et al.
Publicado: (2017)

Determination of complete chromosomal haplotypes by bulk DNA sequencing
por: Tourdot, Richard W., et al.
Publicado: (2021)

Linking abnormal mitosis to the acquisition of DNA damage
por: Ganem, Neil J., et al.
Publicado: (2012)

Computational error and complexity in science and engineering: computational error and complexity
por: Lakshmikantham, Vangipuram, et al.
Publicado: (2005)

Chromosome Segregation Errors Generate a Diverse Spectrum of Simple and Complex Genomic Rearrangements
por: Ly, Peter, et al.
Publicado: (2019)

Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments
por: Gutierrez, Abraham, et al.
Publicado: (2020)

Single-cell chromatin accessibility and lipid profiling reveals SCD1-dependent metabolic shift in adipocytes induced by bariatric surgery
por: Harlan, Blaine, et al.
Publicado: (2021)

Defense genes missing from the flight division
por: Magor, Katharine E., et al.
Publicado: (2013)

Cognitive control of conscious error awareness: error awareness and error positivity (Pe) amplitude in moderate-to-severe traumatic brain injury (TBI)
por: Logan, Dustin M., et al.
Publicado: (2015)

Analyses of Landing Mechanics in Division I Athletes Using the Landing Error Scoring System
por: James, Joan, et al.
Publicado: (2015)

Impact of next-generation sequencing error on analysis of barcoded plasmid libraries of known complexity and sequence
por: Deakin, Claire T., et al.
Publicado: (2014)

Comparative analyses of error handling strategies for next-generation sequencing in precision medicine
por: F. Löchel, Hannah, et al.
Publicado: (2020)

A Mechanism Linking Extra Centrosomes to Chromosomal Instability
por: Ganem, Neil J., et al.
Publicado: (2009)

Sample Training Based Wildfire Segmentation by 2D Histogram θ-Division with Minimum Error
por: Zhao, Jianhui, et al.
Publicado: (2013)

Adaptive Digital Hologram Binarization Method Based on Local Thresholding, Block Division and Error Diffusion
por: Cheremkhin, Pavel A., et al.
Publicado: (2022)

Active cell divisions generate fourfold orientationally ordered phase in living tissue
por: Cislo, Dillon J., et al.
Publicado: (2023)

2D position sensitive microstrip sensors with charge division along the strip: Studies on the position measurement error
por: Bassignana, D, et al.
Publicado: (2013)

2D Position Sensitive Microstrip Sensors with Charge Division Along the Strip: Studies on the position measurement error
por: Bassignana, D, et al.
Publicado: (2013)

Spontaneous Prediction Error Generation in Schizophrenia
por: Yamashita, Yuichi, et al.
Publicado: (2012)

Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions
por: Beeharry, Neil, et al.
Publicado: (2015)

Asymmetric Cell Division of Fibroblasts is An Early Deterministic Step to Generate Elite Cells during Cell Reprogramming
por: Song, Yang, et al.
Publicado: (2021)

Quantifying the Relative Contributions of Divisive and Subtractive Feedback to Rhythm Generation
por: Tabak, Joël, et al.
Publicado: (2011)

Publications and services of the Cryogenics Division, 1953-1973
por: Johnson, Victor J, et al.
Publicado: (1973)

Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division
por: Maia, Ana Rita R., et al.
Publicado: (2018)

Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions
por: Liu, Xinhui, et al.
Publicado: (2022)

Divisibility patterns of natural numbers on a complex network
por: Shekatkar, Snehal M., et al.
Publicado: (2015)

Genetic mapping of complex traits by minimizing integrated square errors
por: Wu, Song, et al.
Publicado: (2012)

Generational difference of refractive error in the baseline study of the Beijing Myopia Progression Study
por: Liang, Yuan Bo, et al.
Publicado: (2013)

Benchmarking of computational error-correction methods for next-generation sequencing data
por: Mitchell, Keith, et al.
Publicado: (2020)

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B
por: Tien, Jerry F., et al.
Publicado: (2010)

Correlation of Head Impacts to Change in Balance Error Scoring System Scores in Division I Men’s Lacrosse Players
por: Miyashita, Theresa L., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s7trs0n595j41ecb2shr475kpj