Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models

Senile plaques frequently contain Aβ-pE(3), a N-terminally truncated Aβ species that is more closely linked to AD compared to other Aβ species. Tau protein is highly phosphorylated at several residues in AD, and specifically phosphorylation at Ser202/Thr205 is known to be increased in AD. Several st...

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Detalles Bibliográficos
Autores principales: Neddens, Joerg, Daurer, Magdalena, Flunkert, Stefanie, Beutl, Kerstin, Loeffler, Tina, Walker, Lauren, Attems, Johannes, Hutter-Paier, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347153/
https://www.ncbi.nlm.nih.gov/pubmed/32645028
http://dx.doi.org/10.1371/journal.pone.0235543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347153/
https://www.ncbi.nlm.nih.gov/pubmed/32645028
http://dx.doi.org/10.1371/journal.pone.0235543

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