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Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models
Senile plaques frequently contain Aβ-pE(3), a N-terminally truncated Aβ species that is more closely linked to AD compared to other Aβ species. Tau protein is highly phosphorylated at several residues in AD, and specifically phosphorylation at Ser202/Thr205 is known to be increased in AD. Several st...
Autores principales: | Neddens, Joerg, Daurer, Magdalena, Flunkert, Stefanie, Beutl, Kerstin, Loeffler, Tina, Walker, Lauren, Attems, Johannes, Hutter-Paier, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347153/ https://www.ncbi.nlm.nih.gov/pubmed/32645028 http://dx.doi.org/10.1371/journal.pone.0235543 |
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