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Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia
The vasculature within a tumor is highly disordered both structurally and functionally. Endothelial cells that comprise the vasculature are poorly connected causing vessel leakage and exposing the endothelium to a hypoxic microenvironment. Therefore, most anti-angiogenic therapies are generally inef...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347218/ https://www.ncbi.nlm.nih.gov/pubmed/32645038 http://dx.doi.org/10.1371/journal.pone.0232072 |