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Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia

The vasculature within a tumor is highly disordered both structurally and functionally. Endothelial cells that comprise the vasculature are poorly connected causing vessel leakage and exposing the endothelium to a hypoxic microenvironment. Therefore, most anti-angiogenic therapies are generally inef...

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Detalles Bibliográficos
Autores principales:	Cohen, Emily B., Geck, Renee C., Toker, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347218/ https://www.ncbi.nlm.nih.gov/pubmed/32645038 http://dx.doi.org/10.1371/journal.pone.0232072

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