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Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans

Mycolactones, macrolide cytotoxins, are key virulence factors of Mycobacterium ulcerans, the etiological agent of the chronic necrotizing skin disease Buruli ulcer. There is urgent need for a simple point-of-care laboratory test for Buruli ulcer and mycolactone represents a promising target for the...

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Detalles Bibliográficos
Autores principales: Warryn, Louisa, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, Schäfer, Anja, Ruf, Marie-Thérèse, Ruggli, Nicolas, Altmann, Karl-Heinz, Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347236/
https://www.ncbi.nlm.nih.gov/pubmed/32589646
http://dx.doi.org/10.1371/journal.pntd.0008357