Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data

Adaptive immune receptor repertoire sequencing (AIRR-Seq) offers the possibility of identifying and tracking B cell clonal expansions during adaptive immune responses. Members of a B cell clone are descended from a common ancestor and share the same initial V(D)J rearrangement, but their B cell rece...

Descripción completa

Detalles Bibliográficos
Autores principales: Nouri, Nima, Kleinstein, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347241/
https://www.ncbi.nlm.nih.gov/pubmed/32574157
http://dx.doi.org/10.1371/journal.pcbi.1007977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347241/
https://www.ncbi.nlm.nih.gov/pubmed/32574157
http://dx.doi.org/10.1371/journal.pcbi.1007977

Ejemplares similares