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Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones

Diffusible small molecule microbial hormones drastically alter the expression profiles of antibiotics and other drugs in actinobacteria. For example, avenolide (a butenolide) regulates the production of avermectin, derivatives of which are used in the treatment of river blindness and other parasitic...

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Detalles Bibliográficos
Autores principales: Kapoor, Iti, Olivares, Philip, Nair, Satish K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347384/
https://www.ncbi.nlm.nih.gov/pubmed/32510324
http://dx.doi.org/10.7554/eLife.57824