Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie diet

OBJECTIVE: Food intake normally stimulates release of satiety and insulin-stimulating intestinal hormones, such as glucagon-like peptide (GLP)-1. This response is blunted in obese insulin resistant subjects, but is rapidly restored following Roux-en-Y gastric bypass (RYGB) surgery. We hypothesised t...

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Detalles Bibliográficos
Autores principales: Wallenius, Ville, Elias, Erik, Elebring, Erik, Haisma, Bauke, Casselbrant, Anna, Larraufie, Pierre, Spak, Emma, Reimann, Frank, le Roux, Carel W, Docherty, Neil G, Gribble, Fiona M, Fändriks, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Small Bowel
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347417/
https://www.ncbi.nlm.nih.gov/pubmed/31753852
http://dx.doi.org/10.1136/gutjnl-2019-319372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347417/
https://www.ncbi.nlm.nih.gov/pubmed/31753852
http://dx.doi.org/10.1136/gutjnl-2019-319372

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