SARS-CoV and SARS-CoV-2 main protease residue interaction networks change when bound to inhibitor N3

COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2. SARS-CoV-2 has many similarities with SARS-CoV. Both viruses rely on a protease called the main protease, or M(pro), for replication. Therefore, inhibiting M(pro) may be a successful strategy for treating COVID-19. Structures of...

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Detalles Bibliográficos
Autor principal: Griffin, Jeddidiah W.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347504/
https://www.ncbi.nlm.nih.gov/pubmed/32653646
http://dx.doi.org/10.1016/j.jsb.2020.107575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347504/
https://www.ncbi.nlm.nih.gov/pubmed/32653646
http://dx.doi.org/10.1016/j.jsb.2020.107575

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