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dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye
The ciliary marginal zone (CMZ) of the zebrafish retina contains a population of actively proliferating resident stem cells, which generate retinal neurons throughout life. The maintenance methyltransferase, dnmt1, is expressed within the CMZ. Loss of dnmt1 function results in gene misregulation and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347529/ https://www.ncbi.nlm.nih.gov/pubmed/32647199 http://dx.doi.org/10.1038/s41598-020-68016-z |