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Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges

Colon cancer inter-tumour heterogeneity is installed on multiple levels, ranging from (epi)genetic driver events to signalling pathway rewiring reflected by differential gene expression patterns. Although the existence of heterogeneity in colon cancer has been recognised for a longer period of time,...

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Detalles Bibliográficos
Autores principales: Buikhuisen, Joyce Y., Torang, Arezo, Medema, Jan Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347540/
https://www.ncbi.nlm.nih.gov/pubmed/32647253
http://dx.doi.org/10.1038/s41389-020-00250-6