Polymerized human hemoglobin facilitated modulation of tumor oxygenation is dependent on tumor oxygenation status and oxygen affinity of the hemoglobin-based oxygen carrier

Administration of hemoglobin-based oxygen carriers (HBOCs) into the systemic circulation is a potential strategy to relieve solid tumor hypoxia in order to increase the effectiveness of chemotherapeutics. Previous computational analysis indicated that the oxygen (O(2)) status of the tumor and HBOC O...

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Detalles Bibliográficos
Autores principales: Belcher, Donald A., Lucas, Alfredo, Cabrales, Pedro, Palmer, Andre F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347553/
https://www.ncbi.nlm.nih.gov/pubmed/32647211
http://dx.doi.org/10.1038/s41598-020-68190-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347553/
https://www.ncbi.nlm.nih.gov/pubmed/32647211
http://dx.doi.org/10.1038/s41598-020-68190-0

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