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Polymerized human hemoglobin facilitated modulation of tumor oxygenation is dependent on tumor oxygenation status and oxygen affinity of the hemoglobin-based oxygen carrier

Administration of hemoglobin-based oxygen carriers (HBOCs) into the systemic circulation is a potential strategy to relieve solid tumor hypoxia in order to increase the effectiveness of chemotherapeutics. Previous computational analysis indicated that the oxygen (O(2)) status of the tumor and HBOC O...

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Detalles Bibliográficos
Autores principales:	Belcher, Donald A., Lucas, Alfredo, Cabrales, Pedro, Palmer, Andre F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347553/ https://www.ncbi.nlm.nih.gov/pubmed/32647211 http://dx.doi.org/10.1038/s41598-020-68190-0

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