INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module

The Integrator complex processes 3′-ends of spliceosomal small nuclear RNAs (snRNAs). Furthermore, it regulates transcription of protein coding genes by terminating transcription after unstable pausing. The molecular basis for Integrator’s functions remains obscure. Here, we show that INTS10, Asunde...

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Detalles Bibliográficos
Autores principales: Sabath, Kevin, Stäubli, Melanie L., Marti, Sabrina, Leitner, Alexander, Moes, Murielle, Jonas, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347597/
https://www.ncbi.nlm.nih.gov/pubmed/32647223
http://dx.doi.org/10.1038/s41467-020-17232-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347597/
https://www.ncbi.nlm.nih.gov/pubmed/32647223
http://dx.doi.org/10.1038/s41467-020-17232-2

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