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Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites

Lipopolysaccharide (LPS) is a critical component of the outer membrane (OM) of many Gram-negative bacteria. LPS is translocated to the OM by the LPS transport (Lpt) system. In the human pathogen Pseudomonas aeruginosa, the periplasmic Lpt component, LptH, is essential for LPS transport, planktonic a...

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Detalles Bibliográficos
Autores principales: Scala, Romina, Di Matteo, Adele, Coluccia, Antonio, Lo Sciuto, Alessandra, Federici, Luca, Travaglini-Allocatelli, Carlo, Visca, Paolo, Silvestri, Romano, Imperi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347655/
https://www.ncbi.nlm.nih.gov/pubmed/32647254
http://dx.doi.org/10.1038/s41598-020-68054-7