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The 3D Brain Unit Network Model to Study Spatial Brain Drug Exposure under Healthy and Pathological Conditions

PURPOSE: We have developed a 3D brain unit network model to understand the spatial-temporal distribution of a drug within the brain under different (normal and disease) conditions. Our main aim is to study the impact of disease-induced changes in drug transport processes on spatial drug distribution...

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Detalles Bibliográficos
Autores principales: Vendel, Esmée, Rottschäfer, Vivi, de Lange, Elizabeth C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347686/
https://www.ncbi.nlm.nih.gov/pubmed/32648115
http://dx.doi.org/10.1007/s11095-020-2760-y