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Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer

INTRODUCTION: Microsatellite instability (MSI) predict response to anti-PD1 immunotherapy in colorectal cancer (CRC). CRCs with MSI have higher infiltration of immune cells related to a better survival. Elevated Microsatellite Alterations at Tetranucleotides (EMAST) is a form of MSI but its associat...

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Detalles Bibliográficos
Autores principales: Watson, Martin M., Lea, Dordi, Gudlaugsson, Einar, Skaland, Ivar, Hagland, Hanne R., Søreide, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347699/
https://www.ncbi.nlm.nih.gov/pubmed/32314040
http://dx.doi.org/10.1007/s00262-020-02573-0