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Early Activation of Myeloid-Derived Suppressor Cells Participate in Sepsis-Induced Immune Suppression via PD-L1/PD-1 Axis

Background: Myeloid derived suppressor cells (MDSCs) have been reported to keep elevating during sepsis. The current study was performed to investigate the immunosuppressive effect of MDSCs and their subsets with the underlying mechanisms. Methods: The immunosuppressive status was manifested by the...

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Detalles Bibliográficos
Autores principales: Ruan, Wei-Shuyi, Feng, Meng-Xiao, Xu, Jia, Xu, Ying-Ge, Song, Cong-Ying, Lin, Li-Ying, Li, Li, Lu, Yuan-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347749/
https://www.ncbi.nlm.nih.gov/pubmed/32719675
http://dx.doi.org/10.3389/fimmu.2020.01299