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Mimicking the Organic and Inorganic Composition of Anabolic Bone Enhances Human Mesenchymal Stem Cell Osteoinduction and Scaffold Mechanical Properties

Engineered bone graft designs have been largely inspired by adult bone despite functionally significant differences from the composition of anabolic bone in both the mineralized and non-mineralized fractions. Specifically, anabolic bone contains hydroxyapatite with ionic substitutions that facilitat...

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Detalles Bibliográficos
Autores principales: Mondragón, Eli, Cowdin, Mitzy, Taraballi, Francesca, Minardi, Silvia, Tasciotti, Ennio, Gregory, Carl A., Kaunas, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347795/
https://www.ncbi.nlm.nih.gov/pubmed/32719790
http://dx.doi.org/10.3389/fbioe.2020.00753