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Thrombin is a therapeutic target for non-small-cell lung cancer to inhibit vasculogenic mimicry formation
Tumor cells transform into endothelial cells by epithelial-to-mesenchymal transition, which is characterized by vasculogenic mimicry (VM). VM not only accelerates tumor progression but also increases drug-induced resistance. However, very little is currently known about the molecular determinants th...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347850/ https://www.ncbi.nlm.nih.gov/pubmed/32647187 http://dx.doi.org/10.1038/s41392-020-0167-1 |