Thrombin is a therapeutic target for non-small-cell lung cancer to inhibit vasculogenic mimicry formation

Tumor cells transform into endothelial cells by epithelial-to-mesenchymal transition, which is characterized by vasculogenic mimicry (VM). VM not only accelerates tumor progression but also increases drug-induced resistance. However, very little is currently known about the molecular determinants th...

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Detalles Bibliográficos
Autores principales: Zhao, Bing, Wu, Mengfang, Hu, Zhihuang, Ma, Yixin, Qi, Wang, Zhang, Yanling, Li, Yaran, Yu, Min, Wang, Huijie, Mo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347850/
https://www.ncbi.nlm.nih.gov/pubmed/32647187
http://dx.doi.org/10.1038/s41392-020-0167-1

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