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Therapeutic potential of fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes as a haemostatic adjuvant for post-cardiopulmonary bypass coagulopathy

Fibrinogen γ-chain peptide-coated, adenosine 5′-diphosphate (ADP)-encapsulated liposomes (H12-ADP-liposomes) are a potent haemostatic adjuvant to promote platelet thrombi. These liposomes are lipid particles coated with specific binding sites for platelet GPIIb/IIIa and encapsulating ADP. They work...

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Detalles Bibliográficos
Autores principales: Ishida, Osamu, Hagisawa, Kohsuke, Yamanaka, Nozomu, Tsutsumi, Koji, Suzuki, Hidenori, Takikawa, Masato, Takeoka, Shinji, Kinoshita, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347858/
https://www.ncbi.nlm.nih.gov/pubmed/32647296
http://dx.doi.org/10.1038/s41598-020-68307-5