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Evaluation of molecular subtypes and clonal selection during establishment of patient-derived tumor xenografts from gastric adenocarcinoma

Patient-derived xenografts (PDX) have emerged as an important translational research tool for understanding tumor biology and enabling drug efficacy testing. They are established by transfer of patient tumor into immune compromised mice with the intent of using them as Avatars; operating under the a...

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Detalles Bibliográficos
Autores principales: Peille, Anne-Lise, Vuaroqueaux, Vincent, Wong, Swee-Seong, Ting, Jason, Klinger, Kerstin, Zeitouni, Bruno, Landesfeind, Manuel, Kim, Woo Ho, Lee, Hyuk-Joon, Kong, Seong-Ho, Wulur, Isabella, Bray, Steven, Bronsert, Peter, Zanella, Nina, Donoho, Greg, Yang, Han-Kwang, Fiebig, Heinz-Herbert, Reinhard, Christoph, Aggarwal, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347869/
https://www.ncbi.nlm.nih.gov/pubmed/32647357
http://dx.doi.org/10.1038/s42003-020-1077-z