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The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain

The development and function of the brain require tight control of gene expression. Genome architecture is thought to play a critical regulatory role in gene expression, but the mechanisms governing genome architecture in the brain in vivo remain poorly understood. Here, we report that conditional k...

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Detalles Bibliográficos
Autores principales: Goodman, Jared V., Yamada, Tomoko, Yang, Yue, Kong, Lingchun, Wu, Dennis Y., Zhao, Guoyan, Gabel, Harrison W., Bonni, Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347877/
https://www.ncbi.nlm.nih.gov/pubmed/32647123
http://dx.doi.org/10.1038/s41467-020-17065-z