Environmental enrichment during forced abstinence from cocaine self-administration opposes gene network expression changes associated with the incubation effect

Environmental enrichment (EE) is a robust intervention for reducing cocaine-seeking behaviors in animals when given during forced abstinence. However, the mechanisms that underlie these effects are not well-established. We investigated the adult male rat transcriptome using RNA-sequencing (RNA-seq)...

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Detalles Bibliográficos
Autores principales: Powell, Gregory L., Vannan, Annika, Bastle, Ryan M., Wilson, Melissa A., Dell’Orco, Michela, Perrone-Bizzozero, Nora I., Neisewander, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347882/
https://www.ncbi.nlm.nih.gov/pubmed/32647308
http://dx.doi.org/10.1038/s41598-020-67966-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347882/
https://www.ncbi.nlm.nih.gov/pubmed/32647308
http://dx.doi.org/10.1038/s41598-020-67966-8

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