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Environmental enrichment during forced abstinence from cocaine self-administration opposes gene network expression changes associated with the incubation effect
Environmental enrichment (EE) is a robust intervention for reducing cocaine-seeking behaviors in animals when given during forced abstinence. However, the mechanisms that underlie these effects are not well-established. We investigated the adult male rat transcriptome using RNA-sequencing (RNA-seq)...
Autores principales: | Powell, Gregory L., Vannan, Annika, Bastle, Ryan M., Wilson, Melissa A., Dell’Orco, Michela, Perrone-Bizzozero, Nora I., Neisewander, Janet L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347882/ https://www.ncbi.nlm.nih.gov/pubmed/32647308 http://dx.doi.org/10.1038/s41598-020-67966-8 |
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