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HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways

Previous studies of global binding patterns identified the epigenetic factor, EZH2, as a regulator of the homeodomain-only protein homeobox (HOPX) gene expression during bone marrow stromal cell (BMSC) differentiation, suggesting a potential role for HOPX in regulating BMSC lineage specification. In...

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Detalles Bibliográficos
Autores principales: Hng, Chee Ho, Camp, Esther, Anderson, Peter, Breen, James, Zannettino, Andrew, Gronthos, Stan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347885/
https://www.ncbi.nlm.nih.gov/pubmed/32647304
http://dx.doi.org/10.1038/s41598-020-68261-2