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CpG-coated Prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma

High-risk neuroblastoma, which is associated with regional and systemic metastasis, is a leading cause of cancer-related mortality in children. Responding to this need for novel therapies for high-risk patients, we have developed a “nanoimmunotherapy,” which combines photothermal therapy (PTT) using...

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Detalles Bibliográficos
Autores principales: Cano-Mejia, Juliana, Shukla, Anshi, Ledezma, Debbie K., Palmer, Erica, Villagra, Alejandro, Fernandes, Rohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348061/
https://www.ncbi.nlm.nih.gov/pubmed/32652470
http://dx.doi.org/10.1016/j.tranon.2020.100823