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Cell Derived Matrix Fibulin-1 Associates With Epidermal Growth Factor Receptor to Inhibit Its Activation, Localization and Function in Lung Cancer Calu-1 Cells

Epidermal Growth Factor Receptor (EGFR) is a known promoter of tumor progression and is overexpressed in lung cancers. Growth factor receptors (including EGFR) are known to interact with extracellular matrix (ECM) proteins, which regulate their activation and function. Fibulin-1 (FBLN1) is a major c...

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Detalles Bibliográficos
Autores principales: Harikrishnan, Keerthi, Joshi, Omkar, Madangirikar, Saili, Balasubramanian, Nagaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348071/
https://www.ncbi.nlm.nih.gov/pubmed/32719793
http://dx.doi.org/10.3389/fcell.2020.00522