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Voltage modulates the effect of μ‐receptor activation in a ligand‐dependent manner

BACKGROUND AND PURPOSE: Various GPCRs have been described as being modulated in a voltage‐dependent manner. Opioid analgesics act via activation of μ receptors in various neurons. As neurons are exposed to large changes in membrane potential, we were interested in studying the effects of depolarizat...

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Detalles Bibliográficos
Autores principales: Ruland, Julia G., Kirchhofer, Sina B., Klindert, Sebastian, Bailey, Chris P., Bünemann, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348086/
https://www.ncbi.nlm.nih.gov/pubmed/32297669
http://dx.doi.org/10.1111/bph.15070