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Activation of μ‐opioid receptors by MT‐45 (1‐cyclohexyl‐4‐(1,2‐diphenylethyl)piperazine) and its fluorinated derivatives

BACKGROUND AND PURPOSE: A fluorinated derivative (2F‐MT‐45) of the synthetic μ‐opioid receptor agonist MT‐45 (1‐cyclohexyl‐4‐(1,2‐diphenylethyl)piperazine) was recently identified in a seized illicit tablet. While MT‐45 is a Class A drug, banned in a number of countries, nothing is known about the p...

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Detalles Bibliográficos
Autores principales: Baptista‐Hon, Daniel T., Smith, Mark, Singleton, Samuel, Antonides, Lysbeth H., Nic Daeid, Niamh, McKenzie, Craig, Hales, Tim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348096/
https://www.ncbi.nlm.nih.gov/pubmed/32246840
http://dx.doi.org/10.1111/bph.15064