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FOXO1 contributes to diabetic cardiomyopathy via inducing imbalanced oxidative metabolism in type 1 diabetes

Forkhead box protein O1 (FOXO1), a nuclear transcription factor, is preferably activated in the myocardium of diabetic mice. However, its role and mechanism in the development of diabetic cardiomyopathy in non‐obese insulin‐deficient diabetes are unclear. We hypothesized that cardiac FOXO1 over‐acti...

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Detalles Bibliográficos
Autores principales: Yan, Dan, Cai, Yin, Luo, Jierong, Liu, Jingjin, Li, Xia, Ying, Fan, Xie, Xiang, Xu, Aimin, Ma, Xiaosong, Xia, Zhengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348139/
https://www.ncbi.nlm.nih.gov/pubmed/32450616
http://dx.doi.org/10.1111/jcmm.15418