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Dabigatran ameliorates airway smooth muscle remodeling in asthma by modulating Yes‐associated protein

Accumulating evidence indicates that thrombin, the major effector of the coagulation cascade, plays an important role in the pathogenesis of asthma. Interestingly, dabigatran, a drug used in clinical anticoagulation, directly inhibits thrombin activity. The aim of this study was to investigate the e...

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Detalles Bibliográficos
Autores principales: Deng, Zhenan, Xie, Haojun, Cheng, Weiying, Zhang, Meihong, Liu, Jie, Huo, Yating, Liao, Yulin, Cheng, Yuanxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348141/
https://www.ncbi.nlm.nih.gov/pubmed/32542982
http://dx.doi.org/10.1111/jcmm.15485