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Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel‐induced peripheral neuropathy

Paclitaxel‐induced peripheral neuropathy (PIPN) is often associated with neuropathic pain and neuroinflammation in the central and peripheral nervous system. Antihypertensive drug losartan, an angiotensin II receptor type 1 (AT1R) blocker, was shown to have anti‐inflammatory and neuroprotective effe...

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Detalles Bibliográficos
Autores principales: Kalynovska, Nataliia, Diallo, Mickael, Sotakova‐Kasparova, Dita, Palecek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348151/
https://www.ncbi.nlm.nih.gov/pubmed/32485058
http://dx.doi.org/10.1111/jcmm.15427