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Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability

Epicardial adipose tissue (EAT) remodelling is closely related to the pathogenesis of atrial fibrillation (AF). We investigated whether metformin (MET) prevents AF‐dependent EAT remodelling and AF vulnerability in dogs. A canine AF model was developed by 6‐week rapid atrial pacing (RAP), and electro...

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Detalles Bibliográficos
Autores principales: Li, Biao, Po, Sunny S., Zhang, Baojian, Bai, Fan, Li, Jiayi, Qin, Fen, Liu, Na, Sun, Chao, Xiao, Yichao, Tu, Tao, Zhou, Shenghua, Liu, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348162/
https://www.ncbi.nlm.nih.gov/pubmed/32441464
http://dx.doi.org/10.1111/jcmm.15407