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New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis

The present study was designed to investigate the role of β‐amyloid (Aβ(1‐42)) in inducing neuronal pyroptosis and its mechanism. Mice cortical neurons (MCNs) were used in this study, LPS + Nigericin was used to induce pyroptosis in MCNs (positive control group), and Aβ(1‐42) was used to interfere w...

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Detalles Bibliográficos
Autores principales: Han, Chenyang, Yang, Yi, Guan, Qiaobing, Zhang, Xiaoling, Shen, Heping, Sheng, Yongjia, Wang, Jin, Zhou, Xiaohong, Li, Wenyan, Guo, Li, Jiao, Qingcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348172/
https://www.ncbi.nlm.nih.gov/pubmed/32521573
http://dx.doi.org/10.1111/jcmm.15439