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Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies

COVID-19 is a clinical syndrome ranging from mild symptoms to severe pneumonia that often leads to respiratory failure, need for mechanical ventilation, and death. Most of the lung damage is driven by a surge in inflammatory cytokines [interleukin-6, interferon-γ, and granulocyte-monocyte stimulatin...

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Detalles Bibliográficos
Autores principales: Bonaventura, Aldo, Vecchié, Alessandra, Wang, Tisha S., Lee, Elinor, Cremer, Paul C., Carey, Brenna, Rajendram, Prabalini, Hudock, Kristin M., Korbee, Leslie, Van Tassell, Benjamin W., Dagna, Lorenzo, Abbate, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348297/
https://www.ncbi.nlm.nih.gov/pubmed/32719685
http://dx.doi.org/10.3389/fimmu.2020.01625